Fasting can have a powerfully positive effect on health and lifespan — effects that can now be delivered in a supplement.
The health benefits of intermittent fasting have been well-documented, ranging from protection against chronic diseases to positively impacting longevity.
Chris Rhodes, Ph.D.
Co-founder and CEO, Mimio Health
“Fasting activates what I call a longevity bioprogram,” explained Chris Rhodes, Ph.D., co-founder and CEO of Mimio Health, a biomimetic human health company. “It optimizes cellular functionality and health for maximum survival.”
Longevity bioprogram
Dr. Rhodes has been studying the benefits of fasting since he was a Ph.D. student at UC Davis. “I wanted to understand what was happening during a fast that could be producing all these amazing benefits and is there a way to recreate it?” he explained. “So, I got my Ph.D. in nutritional biochemistry, doing research on human fasting.”
Fasting turns on survival mechanisms within cells. This process forces the body to be much more efficient with its resources, putting energy into keeping cells healthy and alive for as long as possible — which results in better health and greater longevity.
Fasting in a pill
Dr. Rhodes’ research led to a breakthrough study. “We had men and women fast for 36 hours and looked at the changes that happened in their blood and in their cells,” he explained. “From there, we were able to identify a ‘synergistic combination’ of four molecules that were highly elevated during a fast that, when combined, could recreate all of the benefits we observed from fasting, including increasing lifespan in animal models by 96%.”
Those molecules include:
- Nicotinamide, a form of vitamin B3 and an NAD+ precursor, which turns on fasting-associated pathways that have been shown to extend lifespan.
- Spermidine, an autophagy promoter that boosts cellular cleanup and recycling associated with longevity in humans.
- Palmitoylethanolamide (PEA), which has powerful anti-inflammatory, mood and cognition enhancement, and pain relief effects.
- Oleoylethanolamide (OEA), which promotes cellular fat burning and decreases appetite and cravings.
This discovery directly led to the formation of Mimio Health and their first “fasting mimetic” product called Mimio (the name is a combination of “mimic” and “biology”). Mimio takes the same molecules your body naturally produces during a 36-hour fast and delivers them back as a supplement, recreating fasting at the molecular level — giving you similar benefits without having to fast for 36 hours.
No fasting required
“When you take Mimio, even when you’re eating, you get these fasting-like benefits,” Rhodes noted. “We’ve shown in multiple different clinical trials that with eight weeks of supplementation, we can improve glucose levels, cholesterol levels, decrease cellular stress, and even reduce biological age” Dr. Rhodes explained. “Mimio also has a powerful effect on appetite suppression and metabolic enhancement, reducing cravings and promoting fat burning.”
Even if you already fast, Mimio still offers benefits and helps to supercharge your shorter fasts — anything less than 36 hours — by promoting benefits like autophagy and immune cell resets. and making fasting easier thanks to lowered appetite and improved cognition.
Mimio’s impact on hunger control and craving relief also makes it an ideal way to transition from other weight-control therapies, like GLP-1 drugs. “A huge problem with GLP-1s is that once you go off them, all the cravings come right back,” Rhodes noted. “Mimio is a natural, long-term, sustainable solution that can support similar metabolic and appetite suppression benefits, while also helping to promote cellular longevity.”
Dr. Rhodes is enthusiastic about the future impact of Mimio Health’s approach. “Thanks to our biomimetic research approach, in the same way we learned how to recreate the benefits of fasting, we can create mimetics for other states of the body, like exercise, sleep, or cold exposure,” he said. “We can tease out the underlying beneficial changes and find ways to recreate them on demand.”
To learn more, visit mimiohealth.com
